FOR MORE INFORMATION, CONTACT:

M.J. Wardle

American Cancer Society

Phone: (866) 227-4395

Email: mjwardle@cancer.org

Press Release Prevention Study

FOR IMMEDIATE RELEASE

Major New American Cancer Society Study Looks to Upstate South Carolinafor Participants

Cancer Prevention Study Gives Residents Chance to Have Direct Impact on Cancer

GREENVILLE, SC - April 24, 2007 - The American Cancer Society is looking to Upstate South Carolina residents to play a direct role in improving the lives of future generations by participating in an historic study. The Society will be signing up volunteers for its Cancer Prevention Study-3 (CPS-3) at three Upstate Relay For Life events.

The Greenville, Spartanburg and Anderson Relay For Life events will be three of many sites around the country where individuals can enroll in the new study. All enrollment times are from 5 - 9 p.m. on the following dates of the Relay events:

May 4 Greenville Area Relay For Life at Wade Hampton High School

May 18 Spartanburg Relay For Life at Dorman High School

May 18 Anderson Relay For Life at West Side High School

The study, which will enroll a diverse population of half a million people across the United States, will help researchers better understand the lifestyle, environmental, and genetic factors that cause or prevent cancer, and will further efforts to eliminate cancer as a major health concern for future generations.

Participants must be between the ages of 30 and 65, must never have been diagnosed with cancer, and must be willing to make a long-term commitment to the study. They will be asked to complete a brief written survey, provide a waist measurement, and give a small blood sample at the enrollment site. After that, follow-up surveys will be sent to participants’ homes on a regular basis over the next few decades to update health behavior information.

Researchers will use the data from CPS-3 to build on evidence from a series of American Cancer Society studies that began in the 1950s and involved hundreds of thousands of volunteer participants. The Hammond-Horn Study and previous Cancer Prevention Studies (CPS-I, and CPS-II) have played a major role in understanding cancer prevention and risk, and have contributed significantly to the scientific literature and to the development of public health guidelines and recommendations. Those studies confirmed the link between cigarette smoking and lung cancer, showed that obesity increases the risk of several cancers, and linked aspirin use to a lower death rate from colon cancer. The current study, CPS-II, began in 1982 and is still ongoing. But changes in lifestyle and in the understanding of cancer in the more than two decades since its launch make it important to begin a new cohort.

“It is not an exaggeration to say the American Cancer Society is the only organization likely to be able to successfully recruit and retain such a large-scale population for cancer research,” said Eugenia E. Calle, Ph.D., American Cancer Society director of analytic epidemiology, who is overseeing the study. “We have an excellent record dating back to the 1950’s of conducting these types of studies; we can bring together a world-class research department with a unique community-based volunteer structure like Relay For Life; we can reach diverse populations nationwide who have a shared commitment to cancer research and to eliminating this disease; and because we are a non-profit organization with the ability to partner with volunteers, we can conduct the study for much less than would be possible for the government or a private corporation.”

Theses three Relay For Life events are included with the 64 sites around the country where individuals can enroll in the new study this year, and will be the only time CPS-3 will be enrolling in Upstate this year. Initial enrollment will take 20 to 30 minutes, and the study is expected to produce benefits for decades to come. “While science can do a lot to explain the biology and genetics of cancer, some of the most valuable information we have is a direct result of the contributions of dedicated individuals over several generations,” said Dr. Calle. “We are once again looking to the dedication, compassion, and generosity of Americans to come through and help us provide answers that we know will save lives and improve the outlook for future generations.”

For more information or to learn how to become involved with CPS-3, visit www.cancer.org/cps3 , email cps3@cancer org, or call toll-free 1-888-604-5888.

The American Cancer Society is dedicated to eliminating cancer as a major health problem by saving lives, diminishing suffering and preventing cancer through research, education, advocacy and service. Founded in 1913 and with national headquarters in Atlanta, the Society has 13 regional Divisions and local offices in 3,400 communities, involving millions of volunteers across the United States. For more information anytime, call toll free 1-800-ACS-2345 or visit www.cancer.org.